SORTCERY—A High–Throughput Method to Affinity Rank Peptide Ligands
نویسندگان
چکیده
منابع مشابه
High-throughput method for ranking the affinity of peptide ligands selected from phage display libraries.
The use of phage display peptide libraries allows rapid isolation of peptide ligands for any target selector molecule. However, due to differences in peptide expression and the heterogeneity of the phage preparations, there is no easy way to compare the binding properties of the selected clones, which operates as a major "bottleneck" of the technology. Here, we present the development of a new ...
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ژورنال
عنوان ژورنال: Journal of Molecular Biology
سال: 2015
ISSN: 0022-2836
DOI: 10.1016/j.jmb.2014.09.025